My son and myself have MTHFR so detoxing and methylation are things we need support doing. My son (5) has struggled with anxiety and emotional meltdowns. We have supplemented with different methyl-folate products in the past and seen minor decreases in his behavior but this one has CHANGED him. He has been on it for about 2 months now. Started kindergarten was a cake walk, no fear, anxiety or emotional meltdowns💙. I also take this and notice that I have a more regulated mood. I could not praise this product more.